Hypertension guide

Causes of High Blood Pressure

The Causes of High Blood Pressure explained. Simply put BP is the amount of force that the blood exerts on the of the vessels in the body. Its values fluctuate throughout the day based on several factors. When your BP stays elevated for a period of time, you are deemed to be suffering from hypertension. This is dangerous because it makes the heart work too hard and contributes to hardening of the arteries and other vessels (atherosclerosis).

It also increases the risk of heart disease and stroke. It can result in other conditions such as congestive heart failure, kidney disease, and blindness. A BP level of 140/90 mmHg or higher is considered hypertension. About 66% of people over the age of 65 suffer from hypertension. If your BP is between 120/80 mmHg and 139/89 mmHg, then you suffer from pre-hypertension.

Pre-hypertension means that you don't suffer from hypertension yet but you are likely to develop hypertension in the future unless you adopt the healthy lifestyle changes described on this site. The exact causes of hypertension are not known but several factors and conditions may play a role in its development.

Age (Men: Over 55; Women: Over 65)Abnormal Cholesterol LevelsFamily History of Early Heart DiseaseFamily history of HypertensionTobacco Use or SmokingDiabetesBeing Overweight or ObeseLack of Physical ActivityToo much salt in the dietExcessive Alcohol consumption (More Than 1 to 2 Drinks per Day)StressGeneticsChronic Kidney DiseaseAdrenal and Thyroid Disordersand many more

Hypertension Symptoms

Are you suffering from Hypertension? Hypertension is a serious condition that can lead to coronary heart disease, heart failure, stroke, kidney failure and many more health problems.

High BP Symptoms are not as notable as Low BP Symptoms and hypertension is commonly referred to as the silent killer. Due to this you can suffer from hypertension Symptoms for years before realising that you have the condition. During this time hypertension can cause damage to the heart, kidneys, vessels and other organs in the body.

Hypertension Symptoms and Signs may include:

HeadacheEpistaxis (Nose Bleed)BreathlessnessRinging in Ears (Tinnitus)Insomnia (Sleepiness)Feeling WeakFeeling SleepyConfusionFatigueProfuse SweatingVomitingLoss of LibidoBlurred Vision

Though these Hypertension Symptoms may appear in some patients, most patients experience no Hypertension Symptoms. Below is a Hypertension Table.

Normal: 90-120mmHg/60-80mmHgPre-Hypertension: 120-140mmHg/80-90mmHgHypertension Stage 1: 140-160mmHg/90-100mmHgHypertension Stage 2: 160-180mmHg/100-120mmHgHypertension Crisis: >180mmHg/>120mmHg

Although many people do have some of the Hypertension Symptoms mentioned above many do not have High Blood Pressure Symptoms at all so it is recommended that you know your blood pressure at all times. Whether you test it at home or go for a monthly test at your local physician.

Although many people do have some of the High Blood Pressure Symptoms mentioned above many do not have High Blood Pressure Symptoms at all so it is recommended that you know your blood pressure at all times. Whether you test it at home or go for a monthly test at your local physician.

For more information on High Blood Pressure Symptoms and How to Lower Blood Pressure visit http://www.normalbloodpressure.co.za/

Our website is there to provide you with all the information you need on blood pressure.

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Whether due to increasingly stressful lifestyles and work environments, poor dietary intakes or smoking, levels of heart disease and hypertension are increasing across both the developed world and even in developing countries such as China. As a result the demand for effective heart disease and hypertension medications is also rising. To continue to produce newer and better heart disease and hypertension treatments more and more clinical trials must be performed with more effective parameters.

One of the most common barriers that need to be overcome in clinical trials for heart medication is a phenomenon known as the white coat hypertension effect. This is when unreliable blood pressure readings are gathered in clinical settings. The results are considered unreliable because the clinical environment, where patients or participants are surrounded by nurses, hospital equipment and doctors in white coats and develop hypertension as a result of being in an intimidating or stressful setting.

Controlling for white coat hypertension is an important part of any clinical trials where blood pressure readings are part of the determining data. Inaccurate readings due to white coat hypertension could undermine the actual efficacy of drugs, particularly drugs used to treat hypertension, giving the appearance that they are less effective than they actually are. Due to the high cost of running trials and the financial implications for the production of the drug it is critical to control for white coat hypertension.

One of the simplest ways to control for this kind of hypertension in clinical trials is through ambulatory blood pressure monitoring. This is where the blood pressure of participants is measured at regular intervals over a twenty four hour period. This gives the patient or participant time to adjust to the test environment and give normal readings unaffected by hypertension.

Sometimes this type of ambulatory BP monitoring is inadequate for the requirements of certain clinical trials. The clinical setting may not reflect the normal variation of blood pressure even when the patient has acclimatised to correct for the white coat hypertension effect. In this case the patient or participant can be fitted with a personal blood pressure monitor. This is a device that can continuously monitor blood pressure throughout the day. One advantage of this product is that is can provide a continuous chart that shows fluctuations throughout the day and night. This can reveal information about the participant's blood pressure variation with the circadian rhythm.

Another benefit is that it records the participant's blood pressure as they go about their daily routine. Normal incidents such as being stuck in traffic or enduring a particularly stressful day at work can cause hypertension and other changes. Looking at this information in the course of a trial can show how the product or medicine being trialled effects and is affected by these normal occurrences.

In order to continue producing effective and comprehensive treatments for heart conditions clinical trials must constantly be improved to find better ways of controlling for white coat hypertension and other effects.

Java Clinical provides clinical trials in clinical trials in Europe and Ireland in a variety of therapeutic areas such as hypertension, respiratory, endocrinology, neurology and more. http://www.javacr.com/

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